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APAGARD · 12 products

APAGARD nano-hydroxyapatite toothpaste from Japan

Five formulas, one active ingredient. Pick by how concentrated you want it and how much you brush.

Nano-hydroxyapatiteSangi, JapanPremio · M-Plus · Smokin’

Three APAGARD tubes to start with

APAGARD M-Plus Mild Mint, Single Tube

M-Plus, the classic tube: 125 g, mild mint.

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APAGARD Premio Double Mint, 100 g

Premio, the concentrated one, in double mint.

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APAGARD Royal Toothpaste, 135 g

Royal, the richest in nano mHAP, 135 g.

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The whole range

Twelve tubes and multipacks across five formulas: M-Plus for every day, Premio and Royal for a higher concentration, Renamel for home care between clinic visits, and the stain-removal tubes for coffee, tea, wine and tobacco marks. Sizes run from 100 to 135 grams, in single tubes and packs of two or three.

APAGARD Royal Toothpaste, 135 g

The richest nano-hydroxyapatite paste in the range, 135 g.

  • 4.8 oz, 135 g
  • Highest nano mHAP content in the APAGARD series
  • Twice the nano mHAP of the standard tube
  • Liquid conchiolin, a pearl ingredient
  • Minimal or zero abrasives
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APAGARD Premio Double Mint, Two Tubes

Two tubes of the Premio paste in double mint flavour.

  • 105 g, 3.7 oz
  • Pack of 2
  • Double Mint flavour
  • Sangi's nano-hydroxyapatite (nano-mHAP)
  • No fluoride
  • Part number 4987643122183
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APAGARD M-Plus Mild Mint, Two Tubes

Two tubes of the classic M-Plus paste, mild mint.

  • 125 g, 4.4 oz
  • Pack of 2
  • Mild Mint flavour
  • Standard, longest-selling version of the range
  • No fluoride
  • Part number 4987643504002
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APAGARD M-Plus Mild Mint, Single Tube

One 125 g tube of the classic M-Plus paste.

  • 125 g, 4.4 oz
  • Pack of 1
  • Mild Mint flavour
  • Standard, longest-selling version of the range
  • No fluoride
  • Part number 4987643501049
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APAGARD Premio Brightening, Three Tubes

Three tubes of the higher-strength Premio paste, 105 g each.

  • 105 g, 3.7 oz
  • Set of 3
  • Sangi's nano-hydroxyapatite (nano-mHAP)
  • 2023 version
  • Nano hydroxyapatite high blending
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APAGARD M-Plus Mild Mint, Three Tubes

Three tubes of the classic mild mint M-Plus paste.

  • 125 g, 4.4 oz
  • Pack of 3
  • Mild Mint flavour
  • Standard, longest-selling version of the range
  • No fluoride
  • Part number 4987643504101
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APAGARD Renamel Home Care, 120 g

Home-care paste with the maximum nano mHAP level, 120 g.

  • 120 g, 4.2 ounce
  • Maximum levels of nano mHAP in the range
  • Also contains xylitol, PEG and PVP
  • Intended for home use between clinic visits
  • Suitable for orthodontic brace wearers
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APAGARD M-Plus 130 g, Single Pack

A 130 g tube of the classic mild mint M-Plus paste.

  • 130 g, 4.58 oz
  • Single pack
  • Mild Mint flavour
  • Nano-hydroxyapatite first synthesised by Sangi in 1978
  • Without fluoride
  • Unit count 1
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APAGARD Smokin' Stain Removal, 100 g

Stain-removal paste for tobacco, tea, coffee and wine marks.

  • 100 g, 3.5 oz
  • Stain-removal type
  • Non-abrasive formula
  • Mild Mint flavour
  • Sangi's nano-hydroxyapatite (nano-mHAP)
  • No fluoride
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APAGARD Premio Extra Mint, Two Tubes

Two tubes of Premio in the stronger mint flavour.

  • 3.7 oz, extra mint
  • Set of 2
  • Higher hydroxyapatite content than the standard type
  • Pearl powder in the formula
  • Xylitol among the sweeteners
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APAGARD Smoker Care, Two Tubes

Two tubes of the smoker care paste, mild peppermint.

  • 3.7oz(105g) set of two
  • Set of 2
  • Mild mint, peppermint
  • 2023 version
  • About 0.4 inch of paste per brushing
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APAGARD Premio Double Mint, 100 g

A single 100 g tube of the Premio paste, double mint.

  • 100 g, 3.5 oz
  • Double Mint flavour
  • Sangi's nano-hydroxyapatite (nano-mHAP)
  • No fluoride
  • Pack of 1
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What sits inside every APAGARD tube

APAGARD M-Plus 130 g

Nano-hydroxyapatite instead of fluoride

The active ingredient is Sangi's own nano-hydroxyapatite, nano-mHAP, first synthesized by the company in 1978. It is the building block of tooth enamel, and every tube in this range is fluoride-free.

APAGARD Royal Toothpaste

Concentration marks the formula

M-Plus is the standard tube and the longest-selling of the range. Premio raises the share of the active ingredient, and Royal carries the highest content in the series, twice that of the standard tube.

APAGARD M-Plus Mild Mint

Slow brushing is part of the method

The instruction on the tube asks for 1 to 1.5 cm of paste and three to five minutes of brushing, gently but meticulously, rinsing lightly afterwards so the residue stays in the mouth. It is a different routine from a thirty-second scrub.

APAGARD Smokin' Stain Removal

A tube for each job

Stain removal has its own non-abrasive formula aimed at tobacco, tea, coffee and red wine. Renamel is built for home use after clinical cleaning, bleaching or orthodontic work, and adds xylitol, PEG and PVP.

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What is in the paste and how to use it

One ingredient defines the range: nano-hydroxyapatite, the material teeth are largely made of, synthesized by Sangi in 1978 and sold under the name nano-mHAP. Royal adds liquid conchiolin, an ingredient from pearl, and keeps abrasives to a minimum or leaves them out altogether. Renamel brings xylitol, PEG and PVP alongside the maximum level of nano mHAP in the range.

None of these tubes contains fluoride, and the brand states it plainly on the pack. If a dentist has asked for a fluoride paste, this is not the range to switch to.

Brushing is the part people get wrong. Place a small amount, 1 to 1.5 cm, on the brush. Brush teeth and gums gently but meticulously for about 3-5 minutes, ideally after each meal, three times a day. Rinse lightly and spit out after brushing rather than washing everything away, so what remains keeps working. Renamel adds a second round: brush once, spit, apply more paste and brush again.

Active ingredient Nano-hydroxyapatite (nano-mHAP) by Sangi
Fluoride None in any tube of the range
Sizes 100, 105, 120, 125 and 135 g
Packs Single tubes, packs of two and three
Flavours Mild mint, double mint, extra mint
Brushing time 3-5 minutes, ideally after each meal
APAGARD Royal Toothpaste

Formulas and pack sizes change by listing

The same formula is sold as one tube, two or three, and grams differ between them. Check which pack a listing covers.

Check the current tubes

Which tube suits which routine

APAGARD M-Plus Mild Mint

Every day, for the whole family

M-Plus is the tube most households end up with: mild mint, 125 or 130 grams, and the formula that has been in the range longest. Buy it in twos or threes if more than one person brushes with it.

APAGARD Smokin' Stain Removal

Coffee in the morning, wine in the evening

The stain-removal tubes are aimed at exactly that: marks from tobacco, tea, coffee and red wine, lifted by a non-abrasive formula rather than by scrubbing. Smoker Care covers the same ground in a two-tube set.

APAGARD Renamel Home Care

After the dentist's chair

Renamel is the home-care tube, made for the weeks after mechanical cleaning, bleaching or orthodontic work. It carries the maximum level of nano mHAP in the range and asks for the double brushing routine.

APAGARD Royal Toothpaste

When you want the strongest formula

Royal holds the highest nano mHAP content in the series, twice that of the standard tube, with liquid conchiolin from pearl and almost no abrasives. It is the 135 gram tube at the top of the range.

About the APAGARD range

APAGARD is the toothpaste line built around nano-hydroxyapatite by Sangi, the Japanese company that first synthesized the material in 1978. The whole range runs on that one ingredient, and the tubes differ by how much of it they carry and what else is mixed in.

Five formulas cover the shelf. M-Plus is the everyday tube, Premio raises the concentration, Royal sits at the top of the series, Renamel is the home-care paste for the weeks after dental work, and the stain-removal tubes take on coffee, tea, wine and tobacco.

Sizes and packs matter as much as the formula here, because the same paste is sold as a single 100 gram tube or as three 125 gram ones. Decide on the formula first, then on how long you want it to last.

This catalogue lists the range from the outside. It is not the manufacturer's own shop.

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Questions about these tubes

What is nano-hydroxyapatite and why is it here?
It is the material that tooth enamel is largely made of. Sangi first synthesized it in 1978 and sells it as nano-mHAP, and it is the active ingredient in every tube of this range.
Do any of these contain fluoride?
No. The range is fluoride-free throughout, and the tubes say so on the front. If your dentist has prescribed a fluoride paste, keep to that instead.
How long should brushing take?
Three to five minutes with 1 to 1.5 cm of paste, gently but meticulously over teeth and gums, ideally after each meal. Rinse lightly and spit out after brushing rather than rinsing thoroughly, so what stays in the mouth keeps working.
What separates M-Plus, Premio and Royal?
The share of the active ingredient. M-Plus is the standard tube, Premio is the higher-concentration version, and Royal holds the most nano mHAP in the series, twice the standard tube, plus liquid conchiolin from pearl.
Which tube is for stains from coffee or smoking?
Smokin' and Smoker Care. Both use a non-abrasive formula aimed at marks from tobacco, tea, coffee and red wine, so daily use does not mean scrubbing enamel.
When is Renamel the right choice?
After clinical procedures: mechanical cleaning, bleaching or orthodontic work. It carries the maximum nano mHAP level in the range, adds xylitol, PEG and PVP, and is used with the double brushing technique.

The formulas side by side

Concentration, size and what each tube is aimed at.

APAGARD Formula Size Flavour Aimed at Check price on Amazon
APAGARD M-Plus, single tube Standard 125 g Mild mint Everyday brushing Check price on Amazon
M-Plus 130 g Standard 130 g Mild mint The largest single tube Check price on Amazon
APAGARD Premio, 100 g Higher 100 g Double mint More active ingredient Check price on Amazon
Premio, three tubes Higher 105 g × 3 Mint Stocking up Check price on Amazon
APAGARD Royal, 135 g Highest 135 g Mild mint The top of the range Check price on Amazon
Renamel home care Maximum mHAP 120 g Mint After dental work Check price on Amazon
Smokin' stain removal Standard 100 g Mild mint Tobacco and coffee marks Check price on Amazon

Brush with Japanese nano-hydroxyapatite

APAGARD Premio, M-Plus, Smokin’ and Renamel toothpastes from Sangi. Check the formula, size and today’s price on Amazon.